Gel capsules come in a range of sizes, typically denoted by numbers such as 00, 0, 1, 2, 3, etc. These sizes determine how much substance the capsule can hold, which is essential for both pharmaceuticals and nutraceuticals. Whether you're producing softgel capsules or hard gelatin capsules, understanding the right capsule size for your formulation is key to ensuring proper dosage and consumer experience.
Gel capsules come in various sizes, from 00 (the largest) to 5 (the smallest). The size determines the amount of powder or liquid the capsule can hold, with larger sizes suitable for higher doses and smaller sizes for lower doses. Size 00 is the most commonly used.
Gel Capsule Size Chart
Detailed Description of Gel Capsule Sizes
1.Size 000:
- Capacity: Holds about 1000 mg of powder or 1.37 ml of liquid.
- Use: Ideal for high-dose formulations such as large vitamin supplements, minerals, or other nutraceuticals that require a high volume per dose.
- Dimensions: 26.30 mm in length and 9.50 mm in diameter, making it the largest available size.
2.Size 00:
- Capacity: Holds 400-500 mg of powder or 0.95 ml of liquid.
- Use: Most commonly used size for dietary supplements, vitamins, or pharmaceutical applications that need a moderate dose.
- Dimensions: 23.30 mm in length and 8.50 mm in diameter.
3.Size 0:
- Capacity: Holds 300 mg of powder or 0.68 ml of liquid.
- Use: Often used for medium-dose supplements or concentrated formulas.
- Dimensions: 21.50 mm in length and 7.50 mm in diameter.
4.Size 1:
- Capacity: Holds 200 mg of powder or 0.50 ml of liquid.
- Use: Suitable for lower-dose products or smaller formulations, often used for homeopathic remedies or specific treatments.
- Dimensions: 19.40 mm in length and 6.60 mm in diameter.
5.Size 2:
- Capacity: Holds 150 mg of powder or 0.37 ml of liquid.
- Use: Often used for small-dose medications or products with highly concentrated ingredients.
- Dimensions: 18.20 mm in length and 6.00 mm in diameter.
6.Size 3:
- Capacity: Holds 100 mg of powder or 0.30 ml of liquid.
- Use: Commonly used for micro-doses or concentrated ingredients.
- Dimensions: 16.50 mm in length and 5.40 mm in diameter.
7.Size 4:
- Capacity: Holds 70 mg of powder or 0.20 ml of liquid.
- Use: Ideal for small quantities of highly concentrated powders or micro-doses.
- Dimensions: 15.20 mm in length and 4.80 mm in diameter.
8.Size 5:
- Capacity: Holds 60 mg of powder or 0.13 ml of liquid.
- Use: The smallest size available, typically used for very low-dose or highly potent substances.
- Dimensions: 12.90 mm in length and 4.30 mm in diameter.
Key Considerations When Choosing a Gel Capsule Size
1.Dosage Requirements: Choose a capsule size based on the required dose. Larger capsules (such as 00 and 000) are ideal for high doses, while smaller capsules (3, 4, and 5) are better for lower doses.
2.Formulation Type: If you're using powder or granules, size 00 or 0 might be most suitable. For liquids, you may need a larger capsule (like 00) for proper containment.
3.Swallowability: Larger capsules may be more difficult for some individuals to swallow. Smaller capsules like 3 and 4 are better suited for those who may have difficulty swallowing larger pills.
Can I fill gel capsules with liquids?
Yes, gel capsules can be filled with liquids like oils or suspensions, but larger capsules like 00 or 000 are usually required for liquids due to their higher volume capacity.
What are the benefits of softgel capsules over hard gelatin capsules?
Softgel capsules are typically used for liquid or oil-based products. They are sealed and provide better bioavailability for certain compounds compared to hard capsules, which are ideal for powders.
How do I choose between hard gelatin capsules and softgel capsules?
Choose hard gelatin capsules for powdered or granular substances, while softgel capsules are preferred for oil-based, liquid, or highly viscous formulations.
Can I use multiple smaller capsules to achieve a larger dose?
Yes, multiple smaller capsules (such as 1 or 2) can be used to achieve a larger dose, though it's important to ensure the correct total dosage.
Do capsule sizes differ between manufacturers?
While capsule sizes are standardized, different manufacturers may offer slightly different dimensions or variations. It's essential to confirm capsule size and compatibility before use.
Gel capsules come in different sizes, ranging from 00 (the largest) to 5 (the smallest). The size directly affects the amount of content that the capsule can hold, with larger sizes used for higher doses and smaller sizes for lower doses. Understanding these sizes is crucial for choosing the right capsule for your product's formulation.
Looking for high-quality gel capsule filling machines for your production line?
At Zhejiang Leadtop Pharmaceutical Machinery, we offer a wide range of equipment designed to efficiently fill gel capsules, whether for liquid, powder, or granular substances. Contact us today for more information or a custom quote!